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169 organisms have orthologs with human gene polm. N= indicates the number of cell lines plotted in that lineage.
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Polm mutant mice in polymerase mu mutant mice, hematopoietic cell development is defective in several peripheral and bone marrow cell populations with about a 40% decrease in bone marrow cell. Dna polymerase mu is a polymerase enzyme found in eukaryotes.
Find diseases associated with this biological target and compounds tested against it in bioassay experiments.
Diseases associated with polm include congenital myopathy 2a, typical, autosomal dominant and xeroderma pigmentosum,. The mrna encoding the complete protein is a minor species,. In humans, this protein is encoded by the polm gene.
Explore the crucial role of the polm gene in dna and rna polymerase activity. Learn about its function in transcription, replication, and its implications for genetic research.
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This region constitutes one of the four known fragile sites in.
The polm gene is conserved in chimpanzee, rhesus monkey, cow, mouse, rat, zebrafish, m.oryzae, n.crassa, and frog. Polm (dna polymerase mu) is a protein coding gene. External links uniprot (q9np87) depmap (polm) gtex (polm) pubmed (27434) ncbi gene (27434)
Based on the correspondence of this marker with the gck gene, the polm gene has been mapped within band 7p13.
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